The Overlooked Fertility Factor in PCOS (PMOS): Your Vaginal Microbiome
This post is based on a guest article I wrote for Pelvic Relief. You can read the full version here.

If you have PCOS and you've followed all the advice you've been given, only to be told your tests look "normal" or that there's no clear reason you're not conceiving, you're not alone. I hear this from clients all the time.
One thing I've learned from supporting hundreds of couples is that fertility challenges with PCOS are rarely down to a single factor. They tend to be multi-layered, and one layer that often gets overlooked is the vaginal microbiome.
A quick note on terminology: PCOS has recently been renamed polyendocrine metabolic ovarian syndrome (PMOS). The new name reflects that this is a whole-body hormonal and metabolic condition, not just an ovarian one.
Why the vaginal microbiome matters
The vaginal microbiome is a delicate ecosystem of bacteria and other microbes. When it's healthy and dominated by protective Lactobacillus, it helps keep the environment acidic, protects against infection and supports implantation and early pregnancy.
Research suggests that women with PMOS may be more likely to have lower levels of Lactobacillus and higher levels of inflammatory bacteria. This imbalance, known as vaginal dysbiosis, has been linked to:
Lower implantation rates
Higher miscarriage risk
Greater likelihood of preterm birth
Infections that can be silent
Why PMOS may make this more likely
PMOS can affect more than ovulation. A few of its core features may help explain why the vaginal microbiome can be harder to keep stable:
Insulin resistance. Many women with PMOS have some degree of insulin resistance, which is associated with low-grade inflammation. This may create an environment where inflammatory microbes find it easier to thrive.
Hormonal shifts. Higher androgens and disrupted progesterone patterns can affect immune regulation in the reproductive tract. Even subtle changes may shift vaginal pH.
Metabolic stress. For women in larger bodies, weight-related inflammation may add to this picture, and there's some evidence that body composition can influence the vaginal microbiome too. Not everyone with PMOS is affected in this way, so it's one factor among many.
You can have dysbiosis and feel completely fine
Many people assume that a microbiome imbalance always causes symptoms like odour, discharge or discomfort. In reality, many women feel perfectly well, particularly with low-grade imbalances that don't look like typical bacterial vaginosis or thrush.
That's why I often include vaginal microbiome testing when I'm building a full picture for clients with PMOS who are trying to conceive, whether naturally or with assisted reproduction. It can help to:
Identify bacteria linked to bacterial vaginosis, or Ureaplasma
Check levels of protective Lactobacillus
Explore whether inflammation or pH imbalance could be affecting implantation
Rule out microbial contributors where there has been recurrent miscarriage
Build a targeted plan before conceiving, rather than guessing
The encouraging part
The vaginal microbiome responds well to diet, lifestyle and targeted support. With the right approach, it can often shift towards a more protective, pregnancy-friendly state, which is one reason I enjoy bringing microbiome work into fertility care for PMOS. It's often more manageable than people expect.
Want to find out where you stand?
I've teamed up with Pelvic Relief you can try their vaginal microbiome test at a discounted rate.
Use code YOUNG10 for 10% off: Vaginal Microbiome Test
You can also read the full article on the Pelvic Relief website.
Want support with the bigger picture?
Testing is one piece of the puzzle. If you'd like help with nutrition, supplements, lifestyle and fertility planning, Book your FREE Fertility Review today to find out how tailored support can improve your chances of conception.
Julia Young Nutrition T: 0771 589 0894 info@juliayoungnutrition.com www.juliayoungnutrition.com
Disclaimer: Nutritional Therapy is not a replacement for medical advice, practitioners always refer any client with ‘red flag’ signs or symptoms to their medical professional. The information provided here is general and is not intended to treat, diagnose, prevent or cure any diseases or conditions.




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